TIA – thirdAGE https://thirdage.com healthy living for women + their families Sat, 23 Jul 2016 20:58:26 +0000 en-US hourly 1 https://wordpress.org/?v=5.7.2 Solve the Medical Riddle: She Has Had a Constant Headache for Two Weeks and Her Pupils Are Not the Same Size, Third Week https://thirdage.com/solve-medical-riddle-she-has-had-constant-headache-two-weeks-and-her-pupils-are-not-same-1/ Thu, 15 Oct 2015 04:00:00 +0000 Read More]]> Editor’s note: Welcome to our ThirdAge feature that gives you a chance to play medical sleuth as we share the details of what happened when a patient presented with a problem that stumped the physician at first.

The first week of this riddle, the patient reported her symptoms to her PCP. The doctor proceeded with the examination using the classic S-O-A-P notes as follows:

S=Symptoms or Chief Complaint

O=Objective Findings

A=Assessment or Analysis

P=Treatment Plan or Recommendations

The doctor recognized a potential medical emergency and transferred Chole to the Emergency Department immediately. Last week, we learned what happened when Chloe first arrived in the Emergency Department. This week, we’ll let you know what some people have suggested as possible diagnoses. Next week, the doctor will reveal the actual diagnosis. Then we’ll begin a new riddle for the following month!

Some Guesses as to What the Diagnosis Will Be

“Chloe’s doctor said she had normal blood pressure and pulse, so I guess he’s not worried about what my doctor called ‘pre-stroke’. I had ‘malignant hypertension’, meaning extremely high blood pressure that came on suddenly. They lowered it slowly over a matter of a few hours and I ended up with no organ damage and no stroke. That said, I still wonder if Chloe could have had a little stroke, what they call a transient ischemic attack or TIA. ”

— Julie R.

“Maybe Chloe has an aneurysm. I hope not because that wouldn’t be good news! A brain aneurysm is a bulging area in the wall of a blood vessel. The reason I know is that my brother who is about Chloe’s age had a brain aneurysm. It ruptured and bled and was a life-threatening emergency. His wife got him to urgent care immediately and he pulled through, but it was very frightening. We did learn, though, that many aneurysms don’t rupture and that there are treatments to keep them from rupturing.”

— Kay L.

“Could Chloe have a brain tumor? I imagine that the CT scan would show that. If she does have a tumor, I pray it’s not cancer! Of course even benign brain tumors can be dangerous, but a friend of mine had one and she had surgery to remonve the tumor. She’s hale and hearty four years later, thank goodness!”

— Marlene G.

“Is Chloe positive she never had unequal pupil size before she hit her head? Maybe she never really studied her eyes in the mirror before the headchaes started. I had an enlarged pupil that my eye doctor noticed. She said it was called benign anisocoria and I probably got it from stress. I had just gone trhough a divorce and we were in the middle of a custody battle. I ended up getting the kids. Eventually the anaocoria went away.”

— Susan F.

“Meningitis seems like a possibility to me, although a pretty remote one. Meningitis is an inflammation of the membranes around the brain and the spinal cord. Usually the cause is a viral infection. My daughter had it her freshman year of college. The symptoms were a lot like what Chloe describes. My daughter doesn’t remember hitting her head, though, so Chloe’s problems probably aren’t from an infection. Also, meningitis is most common in young adults, especially those who live in communal settings such as dorms. ”

— Deirdre M.

To be continued . . .

Come back to ThirdAge.com next Thursday when the doctor will reveal the actual diagnosis and treatment plan.

Marie Savard, M.D., a former Medical Contributor for ABC News and a frequent keynote speaker around the world, is one of the most trusted voices on women’s health, wellness, and patient empowerment. She is the author of four books, including one that made the Wall Street Journal list of the best health books of 2009: “Ask Dr. Marie: What Women Need to Know about Hormones, Libido, and the Medical Problems No One Talks About.” Dr. Marie earned a B.S. in Nursing and an M.D. degree at the University of Pennsylvania. She has served as Director of the Center for Women’s Health at the Medical College of Pennsylvania, technical advisor to the United Nations’ Fourth World Conference on Women in Beijing, advisor to the American Board of Internal Medicine Subcommittee on Clinical Competency in Women’s Health, health columnist for Woman’s Day magazine, and senior medical consultant to Lifetime Television’s Strong Medicine. Please visit DrSavard.com.

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A “Game Changing” Treatment for Stroke https://thirdage.com/game-changing-treatment-stroke/ Fri, 01 May 2015 04:00:00 +0000 Read More]]> Researchers have discovered that removing a clot, in combination with standard drug therapy, can be a “game changer” in treating some kinds of stroke.

The findings of the Swift Prime trial (Solitaire With the Intention For Thrombectomy as PRIMary Endovascular treatment) were reported April 17 in the online edition of the New England Journal of Medicine and are scheduled to be published in the journal’s June 11 print edition.

“These findings are a game-changer for how we should treat certain types of stroke,” said Demetrius Lopes, MD, surgical director of the comprehensive stroke center at Rush University Medical Center, in Chicago, and a co-author of the study. “These outcomes are the difference between patients being able to care for themselves after stroke and being dependent.”

According to a news release from Rush, the medical center was one of the 39 centers in the U.S. and Europe that participated in the Swift Prime trial.

More than 795,000 people have a stroke each year, according to the U.S. Centers for Disease Control and Prevention. About 87 percent of these incidents are ischemic strokes, which result from clots in vessels supplying blood to the brain.

The standard treatment for ischemic stroke within the first three to four and a half hours of symptoms is intravenous tissue plasminogen activator (IV tPA), a medication which dissolves the clot. But in the approximately 20 percent of cases in which one of the major arteries is blocked, resulting in a severe stroke, IV tPA alone may not be sufficient to dissolve the clot. If a patient experiencing a severe stroke is brought to a qualified hospital in time, doctors also may be able to perform a minimally invasive procedure called thrombectomy to remove the clot.

During thrombectomy, a neurovascular surgeon threads a catheter through an incision in the patient’s groin, snaking it through the blood vessels and into the brain. The doctor then uses a device attached to the catheter to grab and dislodge the clot and pull it all the way out through the incision.

According to the Rush news release, the Swift Prime study randomly divided patients with severe ischemic strokes into two groups, one receiving IV tPA alone, and the other receiving combination therapy of IV tPA and thrombectomy within six hours of the onset of stroke symptoms. (IV tPA currently is the only treatment for ischemic stroke approved by the U.S. Food and Drug Administration, but the use of thrombectomy is allowed in clinical trials.) In all, 196 patients — 98 in each group — at 39 centers in the U.S. and Canada participated in the study between December 2012 and November 2014.

The study found that the patients who received IV tPA plus thrombectomy exhibited reduced disability, with a functional independence rate of 60 percent compared to 35.5 percent for those patients who received only IV tPA.

The study also found that patients who received thrombectomy had better cerebral blood flow rates: At 27 hours after treatment, 82.8 percent of those patients had blood flow that was 90 percent of normal or better, versus 40.4 percent of patients who only received IV tPA. The study’s findings depart from three previous trials that did not find thrombectomy provided greater benefits than IV tPA alone.

Swift Prime was one of four recent worldwide studies that evaluated newer thombectomy devices and techniques. The result of the first study, reported in the New England Journal in December, found such strong evidence of the benefit of thrombectomy that the other trials were halted.

“Ethically, we can’t deny patients a treatment when we have such strong evidence it’s better for them,” Lopes says. At Rush and other study locations, thrombectomy now is a standard treatment within the first few hours for patients with severe strokes.

But time is still crucial in stroke treatment. However, time remains crucial in stroke treatment. For every minute that a stroke is untreated, a patient loses 1.9 million brain cells and 14 billion connections between brain cells.

“The majority of the positive results of these trials were found in patients treated within four hours, six hours tops,” said James Connors, MD, medical director of the Rush comprehensive stroke c

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